Some commentators are saying that President Obama will "double-down." He'll now follow the FDR strategy of bashing economic royalists, and use that to push even harder for the further nationalization of health care. Banks are not popular now, and neither are insurance companies. Hence he has room to run, focusing on what needs changing, instead of what's in the bill.
That being the case, the opposition probably should follow suit. To block the "the other side wants the status quo" argument, it's time to push for a very simple bill: tort reform, opening the interstate market, a pre-existing conditions fix, and a portability law. Perhaps those aren't exactly the ideas to push, but you get the general idea. It's time to start talking about a genuine bipartisan reform, rather than a transformation and takeover.